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Conformational dynamics of a G protein–coupled receptor helix 8 …

WebGlycosylated peptide [31] and cyclopeptide [32] dendrimers carrying mixed terminal carbohydrates and gold nanorods decorated with two types of glycomimetic polymers … WebG protein–coupled receptors (GPCRs) are the largest and pharmaceutically most important class of membrane proteins encoded in the human genome, characterized by a seven-transmembrane helix architecture and a C-terminal amphipathic helix 8 (H8). In a minority of GPCR structures solved to date, H8 either is absent or adopts an unusual conformation. drake zero pricing

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