Cish isoforms
WebKey features and details Rabbit polyclonal to CISH/CIS - C-terminal Suitable for: IHC-P, WB Reacts with: Rat, Human Isotype: IgG You may also be interested in Protein Recombinant Human CISH/CIS protein (ab117057) Primary Anti-C6orf134/TAT antibody (ab184778) Secondary Goat Anti-Rabbit IgG H&L (HRP) (ab205718) View more associated products … WebMar 21, 2024 · CISH (Cytokine Inducible SH2 Containing Protein) is a Protein Coding gene. Diseases associated with CISH include Bacteremia 2 and Malaria . Among its related pathways are IL3-mediated signaling …
Cish isoforms
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WebAug 1, 2024 · Manipulation of intrinsic factors that inhibit T cell effector function and neoantigen recognition may therefore improve TIL therapy outcomes. We previously identified the cytokine-induced SH2... WebCIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in …
WebSOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. CIS is involved in the negative regulation of cytokines that signal through the JAK-STAT5 pathway such as erythropoietin, prolactin and interleukin 3 … WebSep 25, 2024 · We demonstrate that CISH inhibition can improve the anti-tumor responses of T cells and the ability to efficiently and precisely inactivate CISH using CRISPR, …
WebAnti-CISH antibody produced in mouse. IgG fraction of antiserum, buffered aqueous solution. View Price and Availability. ... Multiple transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq) Immunogen. CISH (NP_659508.1, 1 a.a. ~ 258 a.a) full-length human protein. Sequence. Packaging. 100 μg. WebCIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in …
WebRecombinant Human CISH/CIS protein is a Wheat germ Full length protein 1 to 258 aa range and validated in WB, ELISA, SDS-PAGE. ... and to a lesser extent in lung. The tissue distribution of isoforms 1 and 1B is distinct. Pathway. Protein modification; protein ubiquitination. Sequence similarities. Contains 1 SH2 domain. Contains 1 SOCS box …
WebThe MiTF antibody recognizes serine phosphorylated and non-phosphorylated melanocytic isoforms of microphthalmia. It is useful in identifying Malignant Melanoma, and distinguishing mast cell lesions from lesions of myeloid derivation. A relatively rare class of tumors known as PEComas (tumors showing perivascular epithelioid cell differentiation) … high schools in new albany ohioWebMar 28, 2024 · Cish, participates within a multi-molecular E3 ubiquitin ligase complex, which ubiquitinates target proteins. It has an inhibitory effect on T cell activation mediated by PLC-γ1 regulation, and ... high schools in new braunfels txWebFluorescence in situ hybridization (FISH) technologies enable rapid detection of chromosome aberrations in all manner of tissues, including both fresh and archival specimens. These technologies have gained broad acceptance in the clinical cytogenetic and research communities. how many cups is 2 mlWebThe protein encoded by CISH has a predicted amino acid length of 258 and a mass of 28.7 kDa. There are currently 3 reported isoforms. CISH may also be known by the following … high schools in new jerseyWebOct 14, 2024 · Investigating observations that PD-1 and CISH (cytokine-induced SH2 protein) are expressed with mutual exclusivity in T cells, Palmer and Webber et al. found that CISH acts as an internal regulator … how many cups is 2 liters waterWeb77 rows · CISH has 4,785 functional associations with biological entities spanning 8 categories (molecular profile, organism, functional term, phrase or reference, chemical, … high schools in new canaan ctWebDec 8, 2024 · CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and … how many cups is 2 lb