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Btg2 proliferation

WebThe growth and development of oocyte affect the functional activities of the surrounding somatic cells. These cells are regulated by various types of hormones, proteins, metabolites, and regulatory molecules through gap communication, ultimately leading to the development and maturation of oocytes. The close association between somatic cells and oocytes, … WebBTG2基因含有p53野生型基因的反应元件[11],p73和p53可诱导与人类具有同源性的BTG2基因[12]。利用高密度芯片技术对基因的表达趋势进行研究,发现BTG2基因对细胞的分化、增殖和凋亡起调节作用[13]。

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WebThis study investigates the expression of micro-ribonucleic acid-21 (miRNA-21) and B cell translocation gene 2 (BTG2) in lung cancer cells. We examined the impact of miRNA-21 on biological characteristics of lung cancer cells, such as growth, proliferation, apoptosis, and invasion. The expression of … Protein BTG2 also known as BTG family member 2 or NGF-inducible anti-proliferative protein PC3 or NGF-inducible protein TIS21, is a protein that in humans is encoded by the BTG2 gene (B-cell translocation gene 2) and in other mammals by the homologous Btg2 gene. This protein controls cell cycle … See more A number of studies in vivo have shown that BTG2 expression is associated with the neurogenic asymmetric division in neural progenitor cells. Tis21-GFP has been used as a neurogenic marker because it is not expressed until … See more BTG2 has been shown to inhibit medulloblastoma, the very aggressive tumor of cerebellum, by inhibiting the proliferation and triggering the differentiation of the … See more • Puisieux A, Magaud JP (April 1999). "[Mechanisms of BTG2 activity, a transcriptional target of p53: evidences and hypothesis]". Bulletin du Cancer. 86 (4): 358–64. See more BTG2 has been shown to interact with PRMT1, HOXB9, CNOT8 and HDAC1 HDAC4 and HDAC9. It has also been studied with See more • Human BTG2 genome location and BTG2 gene details page in the UCSC Genome Browser. • Overview of all the structural information … See more cheap cowgirl hats for girls https://tlcky.net

BTG2: a rising star of tumor suppressors (review)

WebFeb 25, 2016 · BTG2 interacts with CAF1 deadenylase through its APRO domain, a defining feature of BTG/Tob factors. ... Importantly, we also show that the interaction of BTG2 with the first RRM domain of PABPC1 is required for BTG2 to control cell proliferation. Publication types Research Support, Non-U.S. Gov't MeSH terms Blotting, Western ... WebA pcDNA3.1-BTG2 eukar … The objective of the study was to investigate the impact of the B cell translocation gene 2 (BTG2) on lung cancer cell growth, proliferation, metastasis, and other biological characteristics and to provide experimental evidence for the biological treatment of human lung cancer. WebFeb 19, 2013 · BTG2 can regulate p53-induced anti-proliferation in tumor cells through the Ras signaling pathway and thus acts as a tumor suppressor . BTG2 may receive … cheap cowgirl hats

M6A Promotes Colorectal Cancer Progression via Regulating the …

Category:M6A Promotes Colorectal Cancer Progression via Regulating the …

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Btg2 proliferation

Emerging role of anti-proliferative protein BTG1 and BTG2

WebJan 8, 2024 · Furthermore, BTG2 suppression might indirectly activate the AKT and ERK-MAPK signaling pathways to mediate the downstream effects of miR-25-3p. Conclusions: This study demonstrates that miR-25-3p promotes proliferation by targeting tumor suppressor BTG2 and may identify new diagnostic and therapeutic targets in TNBC. WebMar 21, 2024 · BTG2 regulates hepatic glucose homeostasis via induction of orphan nuclear receptor Nur77 in diabetic mouse model. pro-apoptotic pathway of CRP-CD32-Nox2-p53 …

Btg2 proliferation

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WebThe B cell translocation gene 1 (BTG1) and BTG2 play a key role in a wide range of cellular activities including proliferation, apoptosis, and cell growth via modulating a variety of central biological steps such as transcription, post-transcriptional, and translation. BTG1 and BTG2 have been identi … WebJun 15, 2024 · Results: MEG3 was lowly expressed in HCC tissues and cells. Overexpression of MEG3 inhibits the proliferation, migration and invasion of HCC cells. MiR-544b can be sponged by MEG3, and overexpression of miR-544b reverses the anti-cancer effect of MEG3. We further confirmed that BTG2 gene is the target gene of miR …

WebDownload scientific diagram Btg2 Downregulation Leads to Increased Microglia Proliferation (A) Normalized read count of genes involved in microglia proliferation (Hammond et al., 2024). WebSep 14, 2024 · The overexpression of BTG2 in A549 cells causes cellular G1 phase arrest but did not affect cell proliferation, accompanied by increased activation of NF-κB. Our data indicate that BTG2 overexpression may trigger an autoregulatory prosurvival NF- κ B pathway, which is resistant to environmental intervention owing to an increased level of …

WebMar 21, 2024 · BTG2 (BTG Anti-Proliferation Factor 2) is a Protein Coding gene. Diseases associated with BTG2 include Diffuse Large B-Cell Lymphoma Activated B-Cell Type … WebMar 8, 2024 · BTG2 maps within the chromosomal segment (1q32), 10 and belongs to the BTG/TOB gene family that regulates cell cycle, cell proliferation, differentiation, and apoptosis. 9,45,46 BTG2 is described as an immediate early gene 47,48 and regulated by p53 activation. 12 Previous studies have reported low expression of BTG2 in a variety of …

WebWe revealed that the mechanism of PRMT5-induced proliferation was partially mediated by BTG downregulation, leading to cell cycle arrest during the G1 phase in HCC cells. Ectopic BTG2 overexpression decreased HCC growth, caused cell cycle arrest at the G1 phase, and downregulated Cyclin D1 and Cyclin E1 protein expression.

WebThe BTG2 expression is downregulated in many human cancers. It is an instantaneous early response gene and plays important roles in cell differentiation, proliferation, DNA … cheap cowling hotelsWebFeb 10, 2024 · BTG2 was identified a target of miR-27a-3p, and silencing BTG2 weakened miR-27a-3p’s effect. Knocking down ADAMTS9-AS2 abolished sh-YTHDF2’s inhibitory effect on cell proliferation and invasion. Finally, overexpressing ADAMTS9-AS2 restrained xenograft growth. M6A reader YTHDF2-mediated degradation of ADAMTS9-AS2 … cutting board custom sizeWebApr 18, 2024 · Recent studies have indicated that BTG2 is highly expressed in heart and skeletal muscle and that the expression levels increase during C2C12 myoblast differentiation . Moreover, BTG2 downregulation blocked C2C12 myoblast differentiation . However, the role of BTG2 in the proliferation and differentiation of myoblasts is not … cheap cowl hoodsWebMar 30, 2024 · Aberrations in FAS and PTEN co-occurred significantly (Q < 0.05), and a significant co-occurrence between PIM1, CD79B, and BTG2 (Q < 0.1) was found, especially in cases that relapsed early (Supplementary Figures S4-S5). cutting board decorative spoons fork cuisineWebHowever, BTG2 may be cancer type-dependent, as overexpression of BTG2 has been demonstrated to suppress the proliferation of pancreatic and lung cancer cells, but promote the proliferation of bladder cancer cells. Since the association between BTG2 and luminal A-subtype breast cancer remains unclear, it is important to understand the biological ... cheap cowhide rugs sydneyWebApr 10, 2024 · Genetic classification helps to disclose molecular heterogeneity and therapeutic implications in diffuse large B-cell lymphoma (DLBCL). Using whole exome/genome sequencing, RNA-sequencing, and ... cutting board definition culinaryWebwww.ncbi.nlm.nih.gov cheap cowgirl wedding dresses