WebThe growth and development of oocyte affect the functional activities of the surrounding somatic cells. These cells are regulated by various types of hormones, proteins, metabolites, and regulatory molecules through gap communication, ultimately leading to the development and maturation of oocytes. The close association between somatic cells and oocytes, … WebBTG2基因含有p53野生型基因的反应元件[11],p73和p53可诱导与人类具有同源性的BTG2基因[12]。利用高密度芯片技术对基因的表达趋势进行研究,发现BTG2基因对细胞的分化、增殖和凋亡起调节作用[13]。
Results - randr19.nist.gov
WebThis study investigates the expression of micro-ribonucleic acid-21 (miRNA-21) and B cell translocation gene 2 (BTG2) in lung cancer cells. We examined the impact of miRNA-21 on biological characteristics of lung cancer cells, such as growth, proliferation, apoptosis, and invasion. The expression of … Protein BTG2 also known as BTG family member 2 or NGF-inducible anti-proliferative protein PC3 or NGF-inducible protein TIS21, is a protein that in humans is encoded by the BTG2 gene (B-cell translocation gene 2) and in other mammals by the homologous Btg2 gene. This protein controls cell cycle … See more A number of studies in vivo have shown that BTG2 expression is associated with the neurogenic asymmetric division in neural progenitor cells. Tis21-GFP has been used as a neurogenic marker because it is not expressed until … See more BTG2 has been shown to inhibit medulloblastoma, the very aggressive tumor of cerebellum, by inhibiting the proliferation and triggering the differentiation of the … See more • Puisieux A, Magaud JP (April 1999). "[Mechanisms of BTG2 activity, a transcriptional target of p53: evidences and hypothesis]". Bulletin du Cancer. 86 (4): 358–64. See more BTG2 has been shown to interact with PRMT1, HOXB9, CNOT8 and HDAC1 HDAC4 and HDAC9. It has also been studied with See more • Human BTG2 genome location and BTG2 gene details page in the UCSC Genome Browser. • Overview of all the structural information … See more cheap cowgirl hats for girls
BTG2: a rising star of tumor suppressors (review)
WebFeb 25, 2016 · BTG2 interacts with CAF1 deadenylase through its APRO domain, a defining feature of BTG/Tob factors. ... Importantly, we also show that the interaction of BTG2 with the first RRM domain of PABPC1 is required for BTG2 to control cell proliferation. Publication types Research Support, Non-U.S. Gov't MeSH terms Blotting, Western ... WebA pcDNA3.1-BTG2 eukar … The objective of the study was to investigate the impact of the B cell translocation gene 2 (BTG2) on lung cancer cell growth, proliferation, metastasis, and other biological characteristics and to provide experimental evidence for the biological treatment of human lung cancer. WebFeb 19, 2013 · BTG2 can regulate p53-induced anti-proliferation in tumor cells through the Ras signaling pathway and thus acts as a tumor suppressor . BTG2 may receive … cheap cowgirl hats